| TITLE: | Disc degeneration
affects the multidirectional flexibility of the lumbar spine.
| AUTHORS:
| Mimura M; Panjabi
MM; Oxland TR; Crisco JJ; Yamamoto I; Vasavada A
| AUTHOR AFFILIATION:
| Department of
Orthopaedics and Rehabilitation, Yale University School of Medicine, New
Haven, Connecticut.
| SOURCE:
| Spine 1994 Jun
15;19(12):1371-80
| CITATION IDS:
| PMID: 8066518 UI:
94345454
| ABSTRACT:
| STUDY DESIGN. An in
vitro biomechanical investigation using human lumbar cadaveric spine
specimens was undertaken to determine any relationship between
intervertebral disc degeneration and nonlinear multidirectional spinal
flexibility. SUMMARY OF BACKGROUND DATA. Previous clinical and
biomechanical studies have not established conclusively such a
relationship. METHODS. Forty-seven discs from 12 whole lumbar spine
specimens were studied under the application of flexion-extension, axial
rotation, and lateral bending pure moments. Three flexibility parameters
were defined (neutral zone (NZ), range of motion (ROM), and neutral zone
ratio (NZR = NZ/ROM)) and correlated with the macroscopic and radiographic
degeneration. RESULTS AND CONCLUSIONS. In flexion-extension, the ROM
decreased and NZR increased with degeneration. In axial rotation, NZ and
NZR increased with degeneration. In lateral bending, the ROM significantly
decreased and the NZR increased with degeneration. In all three loading
directions, the NZR increased, indicating greater joint laxity with
degeneration.
| MAIN MESH HEADINGS:
| Intervertebral
Disk/*pathology | Lumbar Vertebrae/*physiopathology Spinal Diseases/*physiopathology ADDITIONAL MESH
HEADINGS:
| Adult | Biomechanics Comparative Study Data Interpretation, Statistical Human In Vitro Intervertebral Disk/radiography Lumbar Vertebrae/pathology Lumbar Vertebrae/radiography Male Middle Age Rotation Spinal Diseases/pathology Spinal Diseases/radiography 1994/06 1994/15 00:00 PUBLICATION TYPES:
| JOURNAL ARTICLE
| LANGUAGES:
| Eng
| |
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