Brains can be empowered and grow with healthy lifestyles and targeted training. The stemcells of the body are mobilized into action by creating favorable conditions and a climate for growth. Like wise pain, social rejection and inflammation can slow improvement in healing factors and getting a head start by cultivating health brain and body lifestyles has been shown to stave off the onset of certain dementias
Research on cognition that shows transfer of training and increase in quality of life can be very successful when individual differences are professionally assessed and programs targeted to individuals. This is why one size fits all ‘brain training’ shows limited success. The brain requires novelty and positively graded accomplishment to reach full potential. [1-4].
Brain age related deficits are noticed primarily in the prefrontal and parietal cortical regions which tend to shrink as individuals age with men exhibiting more extensive shrinkage than women [5]. These areas are crucial for planning and for connecting input from other brain areas. The areas of shrinkage initially demonstrate increased regional activation. This may be a time sensitive window where neuroplasticity growth factors can be leveraged to best advantage. Combining several strands of behavioral and neuro-imaging evidence, the argument can be made that functional plasticity has the capacity to alter the course of cognitive aging. Losses in regional brain integrity may drive functional reorganization through changes in processing strategies and domain specific cognitive training.
These same deficits can be present in brain injured persons but the route to successful training would take a different though just as effective path.
Factors such as cognitive training, regular exercise, nutrition enrichment and positive relationships can increase Cortical thickness . These findings were first published on animal studies but are also noted in human studies [5-10]. A combination targeted personalized brain and physical training produces specific volume changes in white and grey matter [9]
Physical exercise boosts the brain’s rate of neurogenesis throughout life, while mental exercise increases the rate at which those new brain cells survive and make functional connections into existing neural networks.[7-10] Both physical exercise and the challenge from mental exercise increase the secretion of nerve growth factor, which helps neurons grow and stay healthy.[8-10] This makes sense if we think of how exercise helps to clean out the sludge and provide oxygen so the body can make more effective use of tissues needed for regeneration and repair. In fact scientists are now finding compounds that can increase our stem cells within the body and even then are finding that targeted solutions are needed for optimum stem cell growth health and production [14]
Nyberg found that although older brains exhibit less plasticity than do young brains overall, the benefits of training—particularly domain-specific training—can be substantial and durable [13]. Studies are showing these gains to be of 5 years + More- over, the training benefits were found to be similar to the amount of decline anticipated over 7–14 years [3, 12, and 13].
References
1. Posner, M., & Rothbart M. Educating the human brain. Washington, DC US: American Psychological Association.; 2007:189-208. doi:10.1037/11519-009
2. Jaeggi SM, Buschkuehl M, Jonides J, Perrig WJ. Improving fluid intelligence with training on working memory. Proceedings of the National Academy of Sciences of the United States of America. 2008;105(19):6829-33. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18443283
3. Willis SL, Tennstedt SL, Marsiske M, et al. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA : the journal of the American Medical Association. 2006;296(23):2805-14. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17179457
4. Gordon E, Arns M, Paul RH. Research Report THE INTEGRATE MODEL OF EMOTION, THINKING AND SELF REGULATION: AN APPLICATION TO THE “PARADOX OF AGING”. Thinking. 2008;7(3):367-404.
5. Greenwood PM. Functional plasticity in cognitive aging: review and hypothesis. Neuropsychology. 2007;21(6):657-73. http://www.ncbi.nlm.nih.gov/pubmed/17983277
6. Joseph J, Cole G, Head E, Ingram D. Mark P. Mattson, Sic L. Chan and Wenzhen Duan. Physiological Reviews. 2009:637-672.
7. Kramer AF, Bherer L, Colcombe SJ, Dong W, Greenough WT. Environmental influences on cognitive and brain plasticity during aging. The journals of gerontology. Series A, Biological sciences and medical sciences. 2004;59(9):M940-57.: http://www.ncbi.nlm.nih.gov/pubmed/15472160.
8. Kramer, AF; Erickson KI, Colcombe SJ (2006). “Exercise, cognition, and the aging brain”. J Appl Physiol 101 (4): 1237–42. doi:10.1152/japplphysiol.00500.2006.
9. Valenzuela MJ, Sachdev P, Wen W, Chen X, Brodaty H. Lifespan mental activity predicts diminished rate of hippocampal atrophy. PloS one. 2008;3(7):e2598. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18612379.
10. Ernst C, Olson AK, Pinel JP, Lam RW, Christie BR. Antidepressant effects of exercise: evidence for an adult-neurogenesis hypothesis? Journal of psychiatry & neuroscience : JPN. 2006;31(2):84-92. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16575423
11. Ball K, Edwards JD, Ross La. The impact of speed of processing training on cognitive and everyday functions. The journals of gerontology. Series B, Psychological sciences and social sciences. 2007;62 Spec No(I):19-31. http://www.ncbi.nlm.nih.gov/pubmed/17565162.
12. Willis, SL; SL Tennstedt, M Marsiske, et al. (2006). “Long-term effects of cognitive training on everyday functional outcomes in older adults”. JAMA 296: 2805–14. doi:10.1001/jama.296.23.2805.
13. Nyberg, L. (2005). Cognitive training in healthy aging: A cognitive neuroscience perspective. In R. Cabeza, L. Nyberg, & D. Park (Eds.), Cognitive neuroscience of aging: Linking cognitive and cerebral aging. New York: Oxford University Press.
Retrain Your brain and Increase Joy and Thinking Skills!
By Amy Price PhD
Do you need to get your life back and restore relationships after trauma? Extensive research indicates our brain needs to overcome the negativity bias ingrained through the fight/flight response produced by trauma or social rejection to operate at maximum potential. It is more than positive thinking as the mind has a specific ratio of positive to negative input it accepts plus the input must be genuine to release the feel good chemicals that promote brain learning and healing. Many people involved in an auto crash must fight for insurance rights and social acceptance during an era of limited capacity and chronic pain. All these aspects take a critical toll on the brain and promote inflammation cascades that lead to long term functional loss. The great news is that with targeted brain training in small manageable steps you can get back the edge taken from you though trauma, bad relationships, or serious illness. Your brain wants to work for you!
Clicking on Train Your Brain , Save Your Mind here will take you to a fascinating short video on the power of personal brain optimization and contains a clinicallyvalidated assessment tool. This video is presented by Dr Evian Gordon of Brain Resource Company and speaks about the highly acclaimed wellness program My Brain Solutions. It is well worth investigating, in less than 15 days I showed improvement on several measures of cognition. If you would like to sign-up for MyBrainSolutions please email me ….read on for why training your brain matters…Our minds and brains become so starved for approval and acceptance that we accept input and relationships that are harmful and not genuine.
Your own brain even when it is damaged can pick up emotional cues in 1/20 of a second which will determine how we respond to others. How can you tell the difference between a forced and genuine smile? For a smile ask your self if the eyes crinkle slightly and the pupils enlarge, smiling with only the mouth is not genuine expression. Interestingly this insight has been validated by multiple behavioral, FMRI, GSR and QEEG studies, yet like many insights it is rooted in wisdom passed down from successful individuals who are at peace with themselves. Dr David Whitehouse, an eminent Harvard trained Psychiatrist put is this way ”PEOPLE NOT ONLY SEEK AN EMPOWERING MIND, BUT ONE THAT IS AT PEACE WITH ITSELF”. My Brain Solutions can help you learn to discern emotion and train your brain from a negative to a positive bias and offers a clinically validated personal assessment with a presonalized prescription to increase your brain function. Dr Evian Gordon states in his book ‘The Brain Revolution’ that “THE DIFFERENCE BETWEEN AND EXPERT AND A NOVICE LEARNER IS A MODEL” One critical component of cognitive skill is one’s ability to speedily reframe or re-appraise the circumstances that surround you. People that successfully reframe have better life satisfaction and long term survival rates than those who are fixated on negative events, this ability can be trained.
Research on cognition that shows transfer of training and increase in quality of life is dependent on carefully assessing individual differences with clinically accepted tools which provide personalized training to meet these perimeters[1,2,3,4,]
Learning and novelty are partners yet many brain fitness programs offer rote repetition of weak areas without variation in task or content in a bid to target learning, However research shows us this is not the way meaningful learning occurs. Tasks must be individually challenging to hold engagement and yet structured enough to be doable. Ideally tasks will adapt to changing learning curves to build neuroplasticity. The best learning capitalizes on emotional and intellectual strengths already present while strengthening areas of weakness in a positive atmosphere. For example, teaching a university student mnemonics and concept mapping may make the memory more efficient however teaching an individual with organic damage or early dementia how to remember names and faces with a mnemonic is an exercise in futility.
Specific training alone can lead to plastic changes in the brain as demonstrated by expert Braille readers who show an enlarged hand area and smearing of finger representations in the somatosensory cortex. This result was observed in expert, but not in novice Braille readers suggesting that the training and not the blindness which leads to the changes in cortical representation [5]Similar domain specific results were noted in London taxi drivers and expert violinists. Kramer et al [6] states recruitment of additional brain regions helps performance only if the recruited area complements processing of the task in question. This is likely why rote memorization fails to increase working memory whereas training that targets attentional networks and processing speed increases working memory limits. We are incapable of processing in depth what we have not attended to and our capacity for material attended to is limited by the speed at which we process stimuli.
My Brain Solutions has an inviting Dashboard where you can Empower Your Own Life….See you at the Dashboard!
References:
1. Posner, M., & Rothbart M. Educating the human brain. Washington, DC US: American Psychological Association.; 2007:189-208. doi:10.1037/11519-009
2. Jaeggi SM, Buschkuehl M, Jonides J, Perrig WJ. Improving fluid intelligence with training on working memory. Proceedings of the National Academy of Sciences of the United States of America. 2008;105(19):6829-33. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18443283
3. Willis SL, Tennstedt SL, Marsiske M, et al. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA : the journal of the American Medical Association. 2006;296(23):2805-14. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17179457
4. Gordon E, Arns M, Paul RH. Research Report THE INTEGRATE MODEL OF EMOTION, THINKING AND SELF REGULATION: AN APPLICATION TO THE “PARADOX OF AGING”. Thinking. 2008;7(3):367-404.
5. Greenwood PM. Functional plasticity in cognitive aging: review and hypothesis. Neuropsychology. 2007;21(6):657-73. http://www.ncbi.nlm.nih.gov/pubmed/17983277
6. Kramer AF, Bherer L, Colcombe SJ, Dong W, Greenough WT. Environmental influences on cognitive and brain plasticity during aging. The journals of gerontology. Series A, Biological sciences and medical sciences. 2004;59(9):M940-57.: http://www.ncbi.nlm.nih.gov/pubmed/15472160
Low-level laser light is compressed light of a wavelength from the cold, red part of the spectrum of electromagnetic radiation. It is different from natural light in that it is one precise color; it is coherent (it travels in a straight line), monochromatic (a single wavelength) and polarized (it concentrates its beam in a defined location or spot). These properties allow laser light to penetrate the surface of the skin with no heating effect, no damage to the skin and no known side effects. Rather, laser light directs biostimulative light energy to the body’s cells which the cells then convert into chemical energy to promote natural healing and pain relief.
These are ways laser treatment has been found to help
Speeds Up Tissue Repair: Increased energy to the cells means increased cellular activity for all of the cell’s components that rely on this energy including collagen formation. Speeding up tissue repair means less scar tissue formation.
Increases Endorphins: Endorphins can produce analgesia (pain relief) and feelings of well-being. They are known as the bodies natural pain killers.
Increased Lymphatic Drainage: Studies have shown that cold laser therapy can increase the size of the lymphatic ducts thus facilitating protein waste removal.
Increased Blood Flow: to the tissues because of increased capillary formation. This helps healing. The laser affects deeper tissues as well including muscles and tendons.
Relieve nerve pain and trigger points without surgery or chemicals
By Amy Price PhD
IMS is similar to acupuncture except that the treatment does not rely totally on meridians but is based on a physicians training in anatomy. trigger points and the central nervous system. It can be treatment orientated as well as a useful minimally invasive diagnostic tool for neuropathic muscle pain.
Trauma and chronic pain often produces muscle shortening. These shortened muscles can press on and irritate the nerve. Even though this pressure may seem slight and be difficult to measure it can be the source of excruciating pain. This pressure builds up over time causing all kinds of problems like making the nervous system super sensitive. This can cause sensitivity to pain in other areas of the body. To get an idea of how this works think about wearing a pair of slightly snug shoes. At first you feel nothing but as the day goes on that slight pressure becomes something that can not be ignored. With the shoes you can rip them off and toss them into the trash, but when pressure mounts inside the muscle pushing on the nerve there is nowhere for it to go.
IMS works on the premise that supersensitive area can be desensitized. IMS releases muscle shortening by dry needling the sensitive areas with tiny acupuncture needles. Penetration of a normal muscle is relatively painless however an afflicted muscle responds to the needle with a slight cramping sensation. This stimulates a ’stretch receptor’ which produces a reflex relaxation response resulting in a lengthening of that muscle fiber. The needle also causes an electric potential which travels to the nerve and potentially resets it to normal function. The other thing that happens is the needle produces a minute wound which causes increased blood flow to the area to enhance circulation and initiate healing. For FAQs about IMS or research links click here Does it work? The answer seems to be that for some people it does. For research links New treatments with prolotherapy and adult stem cell treatment may produce results. Diet can help with pain Specific supplements can help ligaments and tendons heal to take the stress off overworked muscles
The ligaments act like duct tape to hold our bones and joints together. When ligaments lose their elasticity the bones and joints move too much and irritate the structures around them. Ligaments provide boundaries for movement. For example when we bend our fingers backwards the ligaments will stop us from pushing them too far back and breaking the bones. It is this way with most of the joints in our bodies. The ligaments cause them to work within a safe range of motion. When one of the ligaments is torn or stretched, the excess movement will cause pain and swelling. In an injured joint and you may notice more popping, cracking or even a grinding feeling. The joint may have become unstable.
In the neck and spine, ligaments are crucial for holding vertebrae together. Spinal ligaments are especially vulnerable to overstretching or tears in a car wreck. If you experience these symptoms after a wreck you may want to be examined for a ligament injury:
• popping, cracking, or grinding in the neck with movement
• pain or spasms that get much worse with activity
• Numbness or tingling into the hand(s) or feet that gets worse with activity or accompanied by popping, cracking, or grinding.
Flexion-extension x-rays, or digital motion x-rays can be a good way to help diagnose ligament instability. A good physician will want to test the spine segment by segment to test for stability and this is an essential step for enabling accurate treatment. The diagram above shows some of the ways ligament pain is referred in the neck area. For referred pain in other body areas look at our dermatome pages
Treatment usually proceeds as follows:
• Specially trained medical practitioners such as Chiropractors or Osteopaths can mobilize any stiff segments that may be overloading the unstable segment
• Posture Training can improve stability, injury can increase tightening of muscle structures which can cause guarding of the painful area. This throws posture off balance and can aggravate instability.
• Strengthen any weak, deep supporting muscles (like multifidus) that may be allowing too much movement. Core strength exercise like modified Pilates with the guidance of a trained physiotherapist can be helpful
• Don’t be talked into mobilizing or manipulating an unstable segment as this can bring a temporary improvement but over time can make things worse. Sometimes bracing is used and while this may seem like a good solution to reduce pain initially prolonged bracing can cause further weakening of the surrounding muscles and later slow recovery.
• Prolotherapy may prove helpful, adult stem cell therapy using your own cells has been reasonably successful in initial trials.
• Surgical stabilization is sometimes used when no other treatment brings improvement.
This page is offered by Simon who became a quadriplegic after a car crash. He has a phenomenal site that helps people understand the complexity of spinal damage and shows how you can choose to do what you want to do in life anyway. Some people let life happen others make things happen. Simon makes things happen! Please visit his site by clicking on the banner on the bottom of this page
This page describes the role of dermatome and myotome locations and how you can have pain at one area when the damage is really somewhere else. We urge people to take a dermatome map into your doctor and show them the pain patterns
Spinal nerves have motor fibers and sensory fibers. The motor fibers innervate certain muscles, while the sensory fibers innervate certain areas of skin. A skin area innervated by the sensory fibers of a single nerve root is known as a dermatome. A group of muscles primarily innervated by the motor fibers of a single nerve root is known as a myotome. Although slight variations do exist, dermatome and myotome patterns of distribution are relatively consistent from person to person.
myotomes-dermatomes by permission Apparelyzed.com
Myotomes
Myotomes – Relationship between the spinal nerve & muscle
Dermatomes – Relationship between the spinal nerve & skin.
Each muscle in the body is supplied by a particular level or segment of the spinal cord and by its corresponding spinal nerve. The muscle, and its nerve make up a myotome. This is approximately the same for every person and are as follows:
C3,4 and 5 supply the diaphragm (the large muscle between the chest and the belly that we use to breath).
C5 also supplies the shoulder muscles and the muscle that we use to bend our elbow .
C6 is for bending the wrist back.
C7 is for straightening the elbow.
C8 bends the fingers.
T1 spreads the fingers.
T1 –T12 supplies the chest wall & abdominal muscles.
L2 bends the hip.
L3 straightens the knee.
L4 pulls the foot up.
L5 wiggles the toes.
S1 pulls the foot down.
S3,4 and 5 supply the bladder. bowel and sex organs and the anal and other pelvic muscles.
Dermatomes
Dermatome Apparelyzed.com used by permission (2009)
Click to enlarge
Dermatome chart – Map
Dermatome is a Greek word which literally means “skin cutting”. A dermatome is an area of the skin supplied by nerve fibers originating from a single dorsal nerve root. The dermatomes are named according to the spinal nerve which supplies them. The dermatomes form into bands around the trunk but in the limbs their organisation is more complex as a result of the dermatomes being “pulled out” as the limb buds form and develop into the limbs during embryological development.
In diagrams or maps, the boundaries of dermatomes are usually sharply defined. However, in life there is considerable overlap of innervation between adjacent dermatomes. Thus, if there is a loss of afferent nerve function by one spinal nerve sensation from the region of skin which it supplies is not usually completely lost as overlap from adjacent spinal nerves occurs: however, there will be a reduction in sensitivity.
Cervical spine showing nerve compression from Wikipedia 2009
Anterior cervical diskectomy is an operation performed on the upper spine (neck) to relieve pressure on one or more nerve roots, or on the spinal cord. The procedure is explained by the words anterior (front), cervical (neck), and diskectomy (cutting out the disc).
ACD is a surgery used as neck and arm pain, among other symptoms, may occur when an intervertebral disc herniates. This happens, either suddenly with injury or slowly over time, when some of the disc’s jelly-like center (the nucleus pulposus) bulges or ruptures through its tough, fibrous outer ring (the annulus fibrosus) and presses on a nerve. When a disc ruptures in the cervical spine, it puts pressure on one or more nerve roots (often called nerve root compression) or on the spinal cord. This pressure causes symptoms in the neck, arms, and even legs. Further pressure may be caused by rough edges of bone, called bone spurs, that naturally build up around some herniated discs. If at all possible it is best to not have this done unless it is pressing on a nerve or the spinal cord, if it is a surgeon will often advise the surgery to avoid further damage to the nerve or spinal cord.
In this operation, the cervical spine is reached through a small incision in the front of your neck. After the soft tissues of the neck are separated, the intervertebral disc and bone spurs are removed. The space left between the vertebrae may be left open or filled with a small piece of bone. In time the vertebrae may fuse, or join together.
If used, the pre-formed bone graft may be obtained from a bone bank. It will not be rejected by your body, because it is avascular (contains no blood cells) or artificial bone protien can be used. In some circumstances, or if your surgeon prefers, the bone graft might instead be removed from your own hip through a second incision.
Anterior cervical diskectomy is not the only solution. A minimally invasive surgery can be done which leaves almost no scar. This link will lead to where you can see a four minute movie of the procedureThe results are best with single level sugery. There are also procedures which are used to patch tears. Autologous stem cell therapy (using your own stem cells) and platelet rich plasma or PRP can be used to fix tears which can be a major source of pain because of the leakage of fluid which irritates the surrounding tissue.
Some people have artificial disks inserted , rather than a diskectomy or fusion. A great place to get information on this option is the ADR support community
Ligament injuries can be more painful and take longer to heal than a broken bone. They are common in traumatic injuries like a car crash, fall or sports injury. A ligament is a tough band of white, fibrous, slightly elastic tissue. They are an essential part of the skeletal joints; binding the bone ends together to prevent dislocation and excessive movement that might cause breakage. Some people like to compare ligaments to duct tape; they hold bones together. Another way of seeing this is to compare ligaments with elastic. Have you ever had favorite clothes where the elastic goes and loses its ability to follow and cling to your body? This is how lax ligaments work in your body. Torn ligaments could be compared to a fan belt in your care or a belt in your clothes dryer or vacuum cleaner, once it tears there is no real way to fix the problem because each time the appliance is used it puts pressure on the belt. Ligaments contain signaling features which tell the bones how much to move. Ligaments also protect the joints and nerves. When these structures are injured, the body works to rebuild them but this is a slow process. A severe ligament tear can take 18 months to heal whereas a broken bone heals in weeks. When the tear is bad and the ligament can’t heal the surrounding muscles work overtime and the nerves do not have the same degree of protection which can lead to chronic pain and atrophy of the surrounding muscles. Severe ligament injuries that can’t heal produce instability in the surrounding structures. When this happens, deep supporting muscles get weak, nerves get irritated (causing more muscle weakness), and joints get inflamed and painful. Ligament injuries may be accompanied by popping and cracking. Tight muscles and bad posture that come from the strain of chronic pain and injury can also cause cracking and popping however in this case the popping and cracking relieves pain and pressure. When popping and cracking makes you feel worse and produces more pain, numbness, or burning; it may be due to instability. Special x-ray techniques called flexion-extension views could be done to rule-out any type of instability. Ligament injury can be treated with prolotherapy and adult stem cell treatment. Ligament repair can treat the injured areas as well but surgery is invasive, there is extensive rehabilitation and considerable down time. Targeted physiotherapy can be used to strengthen the area around the ligament to give it the opportunity to heal. Sometimes bracing is used to rest the area to give it time to recover however this is a temporary solution to reduce pain and used long term can make the situation worse because the surrounding support areas weaken with lack of use. There are some antibiotics such as ciproflaxin which can make hinder ligament repair. Anti-inflammatories can also slow the healing process for ligament injury. Supplements that promote cell health such as vitamin C, Glucosamine, Fish oil supplements and anti-oxidants can help. It is important to have high quality protein in your diet to promote a healthy balance of amino acids which help your cells increase the building blocks needed to heal. Getting enough sleep and regular exercise is important. Stress slows your body’s ability to heal. Learning stress busting techniques or avoiding stressors promotes health.
By Amy Price PhD
My husband underwent adult stem cell therapy in hopes of staving off hip replacement. The technique in the USA was in the early stages and his hip degeneration was acute. In the end he underwent bilateral hip resurfacing in the UK. The procedure was successful and gave him his life back. The UK surgeons were most interested in stem cell therapy and they were working on getting stem cells federally funded particularly for revision surgery which happens when the artificial hip wears out after about fifteen years.
It was exciting to learn about six hip patients who underwent a very creative stem cell procedure in Spire Hospital, Southhampton UK. This procedure could prevent thousands of people from needing to have an artificial hip fitted.
Here is a short breakdown on how they are doing this. Surgeons are using the patient’s own stem cells to rejuvenate the affected bone and donor bone to speed the process. The stem cells are extracted from the patient’s pelvis, purified and cultured in an organic mixture that promotes growth. When the cells had multiplied they were mixed with cleaned, ground-up hip bone from other patients who had hips replaced.Surgeon then excised dead tissue from the ball of the hip and filled the cavity with the mixture of stem cells and donated bone.
Professor Richard Oreffo of Southampton University explains that stem cells send out chemical signals to attract blood vessels. “Bone is a living vibrant tissue. These stem cells generate new tissue and drive new blood vessel formation to bring in nutrients,” he said.
Dr Dunlop is hopeful that this therapy will fix the hip for life. Early reports look promising with good results in 5 out of 6 study participants. The television footage on this was stunning. One patient who had his procedure a year ago looked like he had never experienced a hip problem.
Scientists and doctors are working together to expand this study and to explore the viability of using artificial bone. This would eliminate the problem of donor generated deficits being passed on although I suspect those already in need of new body parts are happy to take their chances.
This news is hot on the heels of research by scientists in New Jersey USA who have successfully isolated nerve growth factors in mesynchemal stem cells and grown them out as published in the latest issue of the Journal of Neurochemisty. Cell biology and Genetic engineering advances may soon provide real answers for those with untreatable neurodegenerative conditions and even those who have sustained brain injury.
Scientist and doctor teams are now considering how this therapy could be applied to other degenerative conditions.
Prolotherapy prompts the body to naturally heal damaged and degenerated tissues. This is not a steroid which can block healing by inhibiting the natural inflammation cycle whereby new cells can regenerate and repair tissue, but a natural substance that promotes healing. In Roman times, soldiers with joint injuries would have those wounds cauterized to promote healing and reduce infection. While modern techniques are much more sophisticated, the concept is the same.
Prolotherapy works by prompting your body’s natural repair mechanisms to heal damaged or degenerated tissues. It’s done when ligaments have been stretched/damaged or torn. This technique can be used in most joints that are unstable. It’s most commonly used for SI joint dysfunction with instability or chronic low back pain. This technique can help repair some of the ligaments and provide normal support to the joint. While most of our daily injuries heal completely, severe ligament tears, degenerated and worn out tissues, and those with a poor blood supply (such as in the knee) don’t usually mend themselves. This is because low grade inflammation is taking place and causing pain but it is not strong enough to signal initiation of the repair process.
Prolotherapy practitioners start by injecting a growth factor stimulant which is not a growth hormone or steroid, but contains a mild irritant such as glucose mixed with local anesthetic to trigger healing response in the damaged area. This otherwise harmless, natural substance, causes a brief period of inflammation 3-5 days after the injection which triggers inflammation that causes the body to release it’s own natural growth factors in the injured tissue.
Most practitioners do these injections in a series, with 3-6 times being considered the norm. This technique can be used in most joints that are unstable. It’s most commonly used for SI joint dysfunction with instability or chronic low back pain. These go to work immediately, directing your body’s natural healing mechanisms to repair damaged and degenerated tissue. The first stage of healing usually takes about a week, but the tissue continues to restore itself for 4-6 weeks after the injection.
It is very important that this treatment is done with fluoroscopy guidance. Fluoroscopy is like an xray movie. Some doctors inject with out xray guidance. For this treatment to be effective it needs to be precisely targeted and done by a practitioner who is getting consistently good results for treatment. It may be good to ask the doctor for the name of a couple of satisfied recipients. They will be able to tell you about the procedure and what to expect as well.
